[Diagnostics and treatment of ischemic heart disease in hemodialysis patients].
نویسندگان
چکیده
Ishemijska bolest srca je klinički sindrom u čijoj osnovi stoji nesklad između jačine protoka krvi kroz koronarne krvne sudove i metaboličkih zahteva miokarda. Prevalencija ishemijske bolesti srca kod bolesnika koji se leče hemodijalizom iznosi 40% . Osnovni razlog za nastanak ishemijske bolesti srca je ateroskleroza koronarnih arterija, a kod bolesnika na hemodijalizi prisutni su brojni faktori rizika koji doprinose aterosklerozi: povišen arterijski krvni pritisak, poremećaj metabolizma lipida, mikroinflamacija, hiperhomocisteinemija, oksidativni stres i sekundarni hiperparatireoidizam . Uz to, kod 27% bolesnika na hemodijalizi simptomi ishemijske bolesti srca posledica su neaterosklerotskih promena koronarnih arterija, koje uključuju promene na malim krvnim sudovima miokarda (arterijska hipertenzija, dijabetes melitus, deponovanja kalcijuma), a nastanku simptoma doprinosi i hipertrofija leve komore (slika 1) 5, .
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ورودعنوان ژورنال:
- Vojnosanitetski pregled
دوره 66 11 شماره
صفحات -
تاریخ انتشار 2009